FGF7 Antibody

• Background:

  The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.

• NCBI Gene ID:

  2252

• Swiss Prot:

  P21781

• Accession Number:

  P21781

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This FGF7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-86 amino acids from the Central region of human FGF7.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  23 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  FGF7

• NCBI Official Name:

  Fibroblast growth factor 7

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lin, C.B., et al. J. Dermatol. Sci. 59 (2) :91-97 (2010)

• Background Reference 02:

  Bando, M., et al. Immunol. Cell Biol. 88 (3) :328-333 (2010)

• Background Reference 03:

  Wang, X., et al. Biomaterials 31 (9) :2542-2548 (2010)

• Background Reference 04:

  Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

• Other Product Names:

  Fibroblast growth factor 7, FGF-7, Heparin-binding growth factor 7, HBGF-7, Keratinocyte growth factor, FGF7, KGF

• Tested Applications:

  WB, IHC-P

• Protein ID:

  122756

• Physical Properties:

  Liquid