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MUTED Antibody

CAT: 0223-55-052Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-052Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1) . Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene.
NCBI Gene ID
63915
Swiss Prot
Q8TDH9
Accession Number
Q8TDH9
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This MUTED antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the Central region of human MUTED.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Pig
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
22 kDa
Fragment
Rabbit Ig
Symbol
BLOC1S5
NCBI Official Name
Biogenesis of lysosome-related organelles complex 1 subunit 5
NCBI Organism
Homo sapiens
Background Reference 01
Morris, D.W., et al. Biol. Psychiatry 63 (1) :24-31 (2008)
Background Reference 02
Oh, J.H., et al. Mamm. Genome 16 (12) :942-954 (2005)
Background Reference 03
Starcevic, M., et al. J. Biol. Chem. 279 (27) :28393-28401 (2004)
Background Reference 04
Li, W., et al. Nat. Genet. 35 (1) :84-89 (2003)
Other Product Names
Biogenesis of lysosome-related organelles complex 1 subunit 5, BLOC-1 subunit 5, Protein Muted homolog, BLOC1S5, MUTED
Tested Applications
WB, IHC-P
Protein ID
34582369
Physical Properties
Liquid

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