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ADAMTS10 Antibody

CAT: 0223-55-037Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-037Size:400 µL
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Background
This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome.
NCBI Gene ID
81794
Swiss Prot
Q9H324
Accession Number
Q9H324
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This ADAMTS10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-240 amino acids from the N-terminal region of human ADAMTS10.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
121 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ADAMTS10
NCBI Official Name
A disintegrin and metalloproteinase with thrombospondin motifs 10
NCBI Organism
Homo sapiens
Background Reference 01
Morales, J., et al. Am. J. Hum. Genet. 85 (5) :558-568 (2009)
Background Reference 02
Ben Yahia, S., et al. J. Hum. Genet. 54 (9) :550-553 (2009)
Background Reference 03
Kutz, W.E., et al. Hum. Mutat. 29 (12) :1425-1434 (2008)
Background Reference 04
Gudbjartsson, D.F., et al. Nat. Genet. 40 (5) :609-615 (2008)
Other Product Names
A disintegrin and metalloproteinase with thrombospondin motifs 10, ADAM-TS 10, ADAM-TS10, ADAMTS-10, 3424-, ADAMTS10
Tested Applications
WB
Protein ID
148887344
Physical Properties
Liquid

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