ADAMTS13 Antibody

• Background:

  This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF) . Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  11093

• Swiss Prot:

  Q76LX8

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 1300-1400 of human ADAMTS13 (NP_620594.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HepG2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 154kDa

• Fragment:

  IgG

• Symbol:

  ADAMTS13

• Positive Control 2:

  LO2

• Positive Control 3:

  22Rv1

• Positive Control 4:

  U-251MG

• Positive Control 5:

  Mouse liver

• NCBI Official Name:

  A disintegrin and metalloproteinase with thrombospondin motifs 13

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  A disintegrin and metalloproteinase with thrombospondin motifs 13, ADAM-TS 13, ADAM-TS13, ADAMTS-13, von Willebrand factor-cleaving protease, vWF-CP, vWF-cleaving protease, ADAMTS13, C9orf8

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid