AGPAT2 Antibody

CAT: 0223-31-341Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-31-341Size:100 µL
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Background
AGPAT2 is a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in its gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance.This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
NCBI Gene ID
10555
Swiss Prot
Q5VUD3
Accession Number
NP_001012745
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AGPAT2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store AGPAT2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
27 kDa, 31 kDa
Applications Notes
AGPAT2 antibody can be used for detection of AGPAT2 by ELISA at 1:312500. AGPAT2 antibody can be used for detection of AGPAT2 by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
AGPAT2
NCBI Official Name
1-acylglycerol-3-phosphate O-acyltransferase 2
NCBI Organism
Homo sapiens
Background Reference 01
Niesporek, S., (2005) Br. J. Cancer 92 (9), 1729-1736.
Other Product Names
AGPAT2, 1-AGPAT2, BSCL, BSCL1, LPAAB, LPAAT-beta
Tested Applications
ELISA, WB
Protein ID
69122971
Physical Properties
Liquid

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