TCF3 Antibody

• Background:

  TCF3 contains 1 basic helix-loop-helix (bHLH) domain. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. TCF3 binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.

• NCBI Gene ID:

  6929

• Swiss Prot:

  P15923

• Accession Number:

  AAA56830

• Host:

  Rabbit

• Reactivity:

  Human, Rat, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TCF3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Cancer

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TCF3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  48 kDa, 68 kDa

• Applications Notes:

  TCF3 antibody can be used for detection of TCF3 by ELISA at 1:62500. TCF3 antibody can be used for detection of TCF3 by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  TCF3

• NCBI Official Name:

  Transcription factor 3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  TCF3, E2A, ITF1, MGC129647, MGC129648, E47, VDIR, TCF-3, bHLHb21

• Tested Applications:

  ELISA, WB

• Protein ID:

  598179

• Physical Properties:

  Liquid