TCF2 Antibody

CAT: 0223-27-551Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-27-551Size:100 µL
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Background
TCF2 encodes transcription factor 2, a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The TCF2 protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1; depending on the TCF2 isoform, the result may be to activate or inhibit transcription of target genes. Mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5) .
NCBI Gene ID
6928
Swiss Prot
P35680
Accession Number
NP_006472
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Zebrafish
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TCF2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TCF2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
45 kDa
Applications Notes
TCF2 antibody can be used for detection of TCF2 by ELISA at 1:312500. TCF2 antibody can be used for detection of TCF2 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
HNF1B
NCBI Official Name
HNF1 homeobox B
NCBI Organism
Homo sapiens
Background Reference 01
Pramfalk, C., (2005) J Lipid Res. 46 (9), 1868-76.
Other Product Names
TCF2, FJHN, HNF2, LFB3, TCF2, HPC11, LF-B3, MODY5, TCF-2, VHNF1, HNF-1B, HNF1beta
Tested Applications
ELISA, WB
Protein ID
6031205
Physical Properties
Liquid

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