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AREB6 Antibody

CAT: 0223-31-162Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-31-162Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Transcription Factor AREB6 / transcription factor 8 /zinc finger homeodomain enhancer-binding protein inhibits interleukin-2 (IL-2) gene expression. May be responsible for transcriptional repression of the IL-2 gene. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type.ZEB1 encodes a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene (MIM 147680) expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site (Williams et al., 1991 [PubMed 1840704]) .
NCBI Gene ID
6935
Swiss Prot
P37275
Accession Number
NP_110378
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AREB6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Signal Transduction, Immunology
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store AREB6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
124 kDa
Applications Notes
AREB6 antibody can be used for detection of AREB6 by ELISA at 1:12500. AREB6 antibody can be used for detection of AREB6 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ZEB1
NCBI Official Name
Zinc finger E-box binding homeobox 1
NCBI Organism
Homo sapiens
Background Reference 01
Gregory, P.A., (2008) Nat. Cell Biol. 10 (5), 593-601.
Other Product Names
AREB6, AREB6, BZP, MGC133261, NIL-2-A, NIL-2A, TCF8, ZEB, ZFHEP, ZFHX1A, FECD6, NIL2A, PPCD3, DELTAEF1
Tested Applications
ELISA, WB
Protein ID
189409128
Physical Properties
Liquid

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