TP53 Antibody

• Background:

  TP53 acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.

• NCBI Gene ID:

  7157

• Swiss Prot:

  P04637

• Accession Number:

  NP_000537

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TP53.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Cell Cycle, Cancer, Apoptosis

• Purification:

  Antibody is purified by Protein A/G affinity chromatography method.

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TP53 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  44 kDa

• Applications Notes:

  TP53 antibody can be used for detection of TP53 by ELISA at 1:62500. TP53 antibody can be used for detection of TP53 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  TP53

• NCBI Official Name:

  Tumor protein p53

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Zakut-Houri, R., et al., (1985) EMBO J. 4: 1251-1255..

• Other Product Names:

  TP53, P53, BCC7, LFS1, TRP53

• Tested Applications:

  ELISA, WB

• Protein ID:

  120407068

• Physical Properties:

  Liquid