CFLAR Antibody

• Background:

  CFLAR might contribute to the carcinogenesis and aggressiveness of endometrial carcinoma and might be a useful prognostic factor in the tumor. CFLAR is specially overexpressed in colon cancers and it might contribute to carcinogenesis of normal colonic mucosa.

• NCBI Gene ID:

  8837

• Swiss Prot:

  O15519

• Accession Number:

  NP_003870

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CFLAR.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction, Immunology, Apoptosis

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CFLAR antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  55 kDa

• Applications Notes:

  CFLAR antibody can be used for detection of CFLAR by ELISA at 1:312500. CFLAR antibody can be used for detection of CFLAR by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CFLAR

• NCBI Official Name:

  CASP8 and FADD-like apoptosis regulator

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kondo, G., et al., (2005) Oncol Rep. 14 (5), 1215-22.

• Other Product Names:

  CFLAR, CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, c-FLIPL, c-FLIPR, c-FLIPS, CASP8AP1

• Tested Applications:

  ELISA, WB

• Protein ID:

  187608571

• Physical Properties:

  Liquid