CCT6B Antibody

• Background:

  CCT6B is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin.This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

• NCBI Gene ID:

  10693

• Swiss Prot:

  Q92526

• Accession Number:

  NP_006575

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CCT6B.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  721_B Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CCT6B antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  58 kDa

• Applications Notes:

  CCT6B antibody can be used for detection of CCT6B by ELISA at 1:312500. CCT6B antibody can be used for detection of CCT6B by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CCT6B

• NCBI Official Name:

  Chaperonin containing TCP1, subunit 6B (zeta 2)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Stirling, P.C., (2006) J. Biol. Chem. 281 (11), 7012-7021.

• Other Product Names:

  CCT6B, CCT-zeta-2, CCTZ-2, Cctz2, TCP-1-zeta-2, TSA303

• Tested Applications:

  ELISA, WB

• Protein ID:

  58331173

• Physical Properties:

  Liquid