ODF2 Antibody

• Background:

  The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. ODF2 is one of the major outer dense fiber proteins.The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. This gene encodes one of the major outer dense fiber proteins. Multiple protein isoforms are encoded by transcript variants of this gene; however, not all isoforms and variants have been fully described.

• NCBI Gene ID:

  4957

• Swiss Prot:

  Q5BJF6-3

• Accession Number:

  NP_002531

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ODF2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ODF2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  89 kDa

• Applications Notes:

  ODF2 antibody can be used for detection of ODF2 by ELISA at 1:312500. ODF2 antibody can be used for detection of ODF2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  ODF2

• NCBI Official Name:

  Outer dense fiber of sperm tails 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Soung, N.K., (2006) Mol. Cell. Biol. 26 (22), 8316-8335.

• Other Product Names:

  ODF2, FLJ44866, MGC111096, MGC9034, ODF2/1, ODF2/2, ODF84, CT134

• Tested Applications:

  ELISA, WB

• Protein ID:

  24430181

• Physical Properties:

  Liquid