CDR2 Antibody

• Background:

  Cdr2 normally sequesters c-Myc in the neuronal cytoplasm, thereby down-regulating c-Myc activity, and suggest a mechanism whereby inhibition of cdr2 function by autoantibodies in PCD may contribute to Purkinje neuronal.

• NCBI Gene ID:

  1039

• Swiss Prot:

  Q01850

• Accession Number:

  NP_001793

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDR2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Cancer

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CDR2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  52 kDa

• Applications Notes:

  CDR2 antibody can be used for detection of CDR2 by ELISA at 1:312500. CDR2 antibody can be used for detection of CDR2 by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CDR2

• NCBI Official Name:

  Cerebellar degeneration-related protein 2, 62kDa

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Balbo, M., (2005) FEMS Microbiol. Lett. 249 (2), 359-366.

• Other Product Names:

  CDR2, CDR62, Yo

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  55770832

• Physical Properties:

  Liquid