CDR2 Antibody

• Background :

  Cdr2 normally sequesters c-Myc in the neuronal cytoplasm, thereby down-regulating c-Myc activity, and suggest a mechanism whereby inhibition of cdr2 function by autoantibodies in PCD may contribute to Purkinje neuronal.

• NCBI Gene ID :

  1039

• Swiss Prot :

  Q01850

• Accession Number :

  NP_001793

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat, Dog

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDR2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Transcription, Cancer

• Purification :

  Antibody is purified by protein A chromatography method.

• Positive Control :

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CDR2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  52 kDa

• Applications Notes :

  CDR2 antibody can be used for detection of CDR2 by ELISA at 1:312500. CDR2 antibody can be used for detection of CDR2 by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  CDR2

• NCBI Official Name :

  Cerebellar degeneration-related protein 2, 62kDa

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Balbo, M., (2005) FEMS Microbiol. Lett. 249 (2), 359-366.

• Other Product Names :

  CDR2, CDR62, Yo

• Tested Applications :

  ELISA, WB, IHC

• Protein ID :

  55770832

• Physical Properties :

  Liquid