OXCT1 Antibody

• Background :

  OXCT1 is a member of the 3-oxoacid CoA-transferase gene family. It is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate.This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.

• NCBI Gene ID :

  5019

• Swiss Prot :

  P55809

• Accession Number :

  NP_000427

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human OXCT1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  Antibody is purified by peptide affinity chromatography method.

• Positive Control :

  Cat. No. 1201 - HeLa Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store OXCT1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  52 kDa

• Applications Notes :

  OXCT1 antibody can be used for detection of OXCT1 by ELISA at 1:62500. OXCT1 antibody can be used for detection of OXCT1 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  OXCT1

• NCBI Official Name :

  3-oxoacid CoA transferase 1

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Fukao, T., (2007) Mol. Genet. Metab. 92 (3), 216-221.

• Other Product Names :

  OXCT1, OXCT, SCOT

• Tested Applications :

  ELISA, WB

• Protein ID :

  4557817

• Physical Properties :

  Liquid