ST14 Antibody

• Background :

  ST14 is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.

• NCBI Gene ID :

  6768

• Swiss Prot :

  Q8WVC1

• Accession Number :

  AAH18146

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ST14.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer

• Purification :

  Antibody is purified by peptide affinity chromatography method.

• Positive Control :

  DLD1 Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ST14 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  46 kDa

• Applications Notes :

  ST14 antibody can be used for detection of ST14 by ELISA at 1:312500. ST14 antibody can be used for detection of ST14 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  ST14

• NCBI Official Name :

  Suppression of tumorigenicity 14 (colon carcinoma)

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  ST14, HAI, MT-SP1, MTSP-1, MTSP1, PRSS14, SNC19, TADG-15, TADG15, TMPRSS14

• Tested Applications :

  ELISA, WB, IHC

• Protein ID :

  17390323

• Physical Properties :

  Liquid