CORIN Antibody

• Background:

  CORIN is a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. CORIN converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.

• NCBI Gene ID:

  10699

• Swiss Prot:

  Q9Y5Q5

• Accession Number:

  EAW93039

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CORIN.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane, Signal Transduction

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CORIN antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  74 kDa, 116 kDa

• Applications Notes:

  CORIN antibody can be used for detection of CORIN by ELISA at 1:312500. CORIN antibody can be used for detection of CORIN by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CORIN

• NCBI Official Name:

  Corin, serine peptidase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CORIN, ATC2, CRN, Lrp4, MGC119742, TMPRSS10, PEE5

• Tested Applications:

  ELISA, WB

• Protein ID:

  119613445

• Physical Properties:

  Liquid