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DDOST Antibody

CAT: 0223-30-207Size: 100 µLDry Ice: NoHazardous: No
CAT#: 30-207Size: 100 µL
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DDOST is a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. DDOST is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.
NCBI Gene ID
1650
Swiss Prot
Q5VWA5
Accession Number
NP_005207
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Zebrafish
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DDOST.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store DDOST antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
46 kDa
Applications Notes
DDOST antibody can be used for detection of DDOST by ELISA at 1:62500. DDOST antibody can be used for detection of DDOST by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
DDOST
NCBI Official Name
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
NCBI Organism
Homo sapiens
Background Reference 01
Shibatani, T., (2005) Biochemistry 44 (16), 5982-5992.
Other Product Names
DDOST, AGE-R1, KIAA0115, MGC2191, OK/SW-cl.45, OST, OST48, WBP1, AGER1, CDG1R, OKSWcl45
Tested Applications
ELISA, WB
Protein ID
20070197
Physical Properties
Liquid

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