NCAPD2 Antibody

• Background:

  NCAPD2 is the regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. NCAPD2 may target the condensin complex to DNA via its C-terminal domain.

• NCBI Gene ID:

  9918

• Swiss Prot:

  Q15021

• Accession Number:

  NP_055680

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NCAPD2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NCAPD2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  157 kDa

• Applications Notes:

  NCAPD2 antibody can be used for detection of NCAPD2 by ELISA at 1:312500. NCAPD2 antibody can be used for detection of NCAPD2 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  NCAPD2

• NCBI Official Name:

  Non-SMC condensin I complex, subunit D2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lee, J.H., (er) Neurogenetics (2008) In press.

• Other Product Names:

  NCAPD2, CAP-D2, CNAP1, KIAA0159, hCAP-D2

• Tested Applications:

  ELISA, WB

• Protein ID:

  178056552

• Physical Properties:

  Liquid