NCAPH2 Antibody

• Background:

  Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 and SMC4, but they contain different sets of non-SMC subunits. NCAPH2 is 1 of 3 non-SMC subunits that define condensin II.Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they contain different sets of non-SMC subunits. NCAPH2 is 1 of 3 non-SMC subunits that define condensin II (Ono et al., 2003 [PubMed 14532007]) .

• NCBI Gene ID:

  29781

• Swiss Prot:

  Q6IBW4

• Accession Number:

  NP_689512

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NCAPH2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1201 - HeLa Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NCAPH2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  68 kDa

• Applications Notes:

  NCAPH2 antibody can be used for detection of NCAPH2 by ELISA at 1:62500. NCAPH2 antibody can be used for detection of NCAPH2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  NCAPH2

• NCBI Official Name:

  Non-SMC condensin II complex, subunit H2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ono, T., (2003) Cell 115 (1), 109-121.

• Other Product Names:

  NCAPH2, 384D8-2, 384D8_6, CAP-H2, MGC15858, MGC18000, MGC2455, MGC4133, MGC5305, MGC8640, hCAP-H2, CAPH2

• Tested Applications:

  ELISA, WB

• Protein ID:

  148368978

• Physical Properties:

  Liquid