HAL Antibody

• Background:

  HAL is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. HAL defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluidsHistidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids.

• NCBI Gene ID:

  3034

• Swiss Prot:

  P42357

• Accession Number:

  NP_002099

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HAL.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. XBL-10409 - Fetal Liver Tissue Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HAL antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  72 kDa

• Applications Notes:

  HAL antibody can be used for detection of HAL by ELISA at 1:312500. HAL antibody can be used for detection of HAL by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  HAL

• NCBI Official Name:

  Histidine ammonia-lyase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Aleman, G., Am. J. Physiol. Endocrinol. Metab. 289 (1), E172-E179 (2005) .

• Other Product Names:

  HAL, HIS, HSTD

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  4504333

• Physical Properties:

  Liquid