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MTUS1 Antibody

CAT: 0223-29-990Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-29-990Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MTUS1 contains a C-terminal domain and is able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. One of the isoforms has been shown to be a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other isoforms may be nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways.This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways.
NCBI Gene ID
57509
Swiss Prot
Q9ULD2-3
Accession Number
NP_065800
Host
Rabbit
Reactivity
Human, Mouse, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MTUS1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MTUS1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
48 kDa, 141 kDa, 136 kDa, 59 kDa
Applications Notes
MTUS1 antibody can be used for detection of MTUS1 by ELISA at 1:1562500. MTUS1 antibody can be used for detection of MTUS1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
MTUS1
NCBI Official Name
Microtubule associated tumor suppressor 1
NCBI Organism
Homo sapiens
Background Reference 01
Nouet, S., (2004) J. Biol. Chem. 279 (28), 28989-28997.
Other Product Names
MTUS1, ATIP, DKFZp586D1519, DKFZp686F20243, FLJ14295, KIAA1288, MP44, MTSG1, ATBP, ICIS
Tested Applications
ELISA, WB
Protein ID
17865632
Physical Properties
Liquid

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