TYR Antibody

• Background :

  TYR is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. It catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone.

• NCBI Gene ID :

  7299

• Swiss Prot :

  P14679

• Accession Number :

  NP_000363

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat, Dog

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TYR.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Membrane, Signal Transduction

• Purification :

  Antibody is purified by protein A chromatography method.

• Positive Control :

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TYR antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  58 kDa

• Applications Notes :

  TYR antibody can be used for detection of TYR by ELISA at 1:1562500. TYR antibody can be used for detection of TYR by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  TYR

• NCBI Official Name :

  Tyrosinase

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Bidinost, C., (2006) Invest. Ophthalmol. Vis. Sci. 47 (4), 1486-1490.

• Other Product Names :

  TYR, OCA1A, OCAIA, ATN, CMM8, OCA1, SHEP3

• Tested Applications :

  ELISA, WB

• Protein ID :

  4507753

• Physical Properties :

  Liquid