GOT2 Antibody

• Background:

  Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.

• NCBI Gene ID:

  2806

• Swiss Prot:

  P00505

• Accession Number:

  NP_002071

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog, Zebrafish

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GOT2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GOT2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  45 kDa

• Applications Notes:

  GOT2 antibody can be used for detection of GOT2 by ELISA at 1:312500. GOT2 antibody can be used for detection of GOT2 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  GOT2

• NCBI Official Name:

  Glutamic-oxaloacetic transaminase 2, mitochondrial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Suzuki, Y., Gene 200 (1-2), 149-156 (1997) .

• Other Product Names:

  GOT2, FLJ40994, kat4, kativ, mitaat, KAT4, KATIV, mitAAT

• Tested Applications:

  ELISA, WB

• Protein ID:

  73486658

• Physical Properties:

  Liquid