GOT1 Antibody

• Background:

  Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.

• NCBI Gene ID:

  2805

• Swiss Prot:

  P17174

• Accession Number:

  P17174

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This GOT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352-381 amino acids from the C-terminal region of human GOT1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  46 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  GOT1

• NCBI Official Name:

  Aspartate aminotransferase, cytoplasmic

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Franke, A., et al. Nat. Genet. 42 (4) :292-294 (2010)

• Background Reference 02:

  Barrett, J.C., et al. Nat. Genet. 41 (12) :1330-1334 (2009)

• Background Reference 03:

  Campos, J., et al. Eur. J. Intern. Med. 20 (3), E53-E56 (2009)

• Other Product Names:

  Aspartate aminotransferase, cytoplasmic, cAspAT, Cysteine aminotransferase, cytoplasmic, Cysteine transaminase, cytoplasmic, cCAT, Glutamate oxaloacetate transaminase 1, Transaminase A, GOT1

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  5902703

• Physical Properties:

  Liquid