CLDN2 Antibody

• Background:

  Members of the claudin protein family, such as CLDN2, are expressed in an organ-specific manner and regulate the tissue-specific physiologic properties of tight junctions.Members of the claudin protein family, such as CLDN2, are expressed in an organ-specific manner and regulate the tissue-specific physiologic properties of tight junctions (Sakaguchi et al., 2002) .

• NCBI Gene ID:

  9075

• Swiss Prot:

  P57739

• Accession Number:

  NP_065117

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLDN2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane, Cancer, Signal Transduction

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CLDN2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  24 kDa

• Applications Notes:

  CLDN2 antibody can be used for detection of CLDN2 by ELISA at 1:312500. CLDN2 antibody can be used for detection of CLDN2 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CLDN2

• NCBI Official Name:

  Claudin 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Escaffit, F., (2005) J. Cell. Physiol. 203 (1), 15-26.

• Other Product Names:

  CLDN2

• Tested Applications:

  ELISA, WB

• Protein ID:

  9966781

• Physical Properties:

  Liquid