BMP2K Antibody

• Background:

  BMP2K is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. BMP2K is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation.This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  55589

• Swiss Prot:

  Q4W5H2

• Accession Number:

  NP_060063

• Host:

  Rabbit

• Reactivity:

  Human, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BMP2K.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store BMP2K antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  74 kDa, 129 kDa

• Applications Notes:

  BMP2K antibody can be used for detection of BMP2K by ELISA at 1:312500. BMP2K antibody can be used for detection of BMP2K by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  BMP2K

• NCBI Official Name:

  BMP2 inducible kinase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Arikawa, T., (2004) J. Cell. Physiol. 200 (3), 400-406.

• Other Product Names:

  BMP2K, BIKE, DKFZp434K0614, DKFZp434P0116, HRIHFB2017

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  38787904

• Physical Properties:

  Liquid