PLUNC Antibody

CAT: 223-29-758Size: 100 µLDry Ice: NoHazardous: No
100 µLSelected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PLUNC is the human homolog of murine plunc and is specifically expressed in the upper airways and nasopharyngeal regions. The exact biological function of this protein is not known, however, it has been suggested to be involved in inflammatory responses to irritants in the upper airways. It may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer.This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The exact biological function of this gene is not known, however, it has been suggested to be involved in inflammatory responses to irritants in the upper airways. It may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only two is known.
NCBI Gene ID
51297
Swiss Prot
Q9NP55
Accession Number
NP_057667
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PLUNC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PLUNC antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
28 kDa, 27 kDa
Applications Notes
PLUNC antibody can be used for detection of PLUNC by ELISA at 1:1562500. PLUNC antibody can be used for detection of PLUNC by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
BPIFA1
NCBI Official Name
BPI fold containing family A, member 1
NCBI Organism
Homo sapiens
Background Reference 01
Zhou, H.D., (2006) Mol. Immunol. 43 (11), 1864-1871.
Other Product Names
PLUNC, LUNX, NASG, SPLUNC1, SPURT, bA49G10.5, PLUNC
Tested Applications
ELISA, WB
Protein ID
7706119
Physical Properties
Liquid