UPB1 Antibody

• Background :

  UPB1 is a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activityThis gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.

• NCBI Gene ID :

  51733

• Swiss Prot :

  Q9UBR1

• Accession Number :

  NP_057411

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat, Dog, Drosophila, Zebrafish, Arabidopsis, C. elegans

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UPB1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Antibody is purified by protein A chromatography method.

• Positive Control :

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store UPB1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  42 kDa

• Applications Notes :

  UPB1 antibody can be used for detection of UPB1 by ELISA at 1:1562500. UPB1 antibody can be used for detection of UPB1 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  UPB1

• NCBI Official Name :

  Ureidopropionase, beta

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Van (2004) Hum. Mol. Genet. 13 (22), 2793-2801.

• Other Product Names :

  UPB1, BUP1

• Tested Applications :

  ELISA, WB

• Protein ID :

  7706509

• Physical Properties :

  Liquid