LOR Antibody

• Background :

  LOR is a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.LOR encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in LOR may be the cause of both Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.

• NCBI Gene ID :

  4014

• Swiss Prot :

  P23490

• Accession Number :

  NP_000418

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LOR.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Antibody is purified by protein A chromatography method.

• Positive Control :

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store LOR antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  35 kDa

• Applications Notes :

  LOR antibody can be used for detection of LOR by ELISA at 1:62500. LOR antibody can be used for detection of LOR by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  LOR

• NCBI Official Name :

  Loricrin

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Giardina, E., Ann. Hum. Genet. 68 (PT 6), 639-645 (2004) .

• Other Product Names :

  LOR, MGC111513, LRN

• Tested Applications :

  ELISA, WB, IHC

• Protein ID :

  109255251

• Physical Properties :

  Liquid