LCAT Antibody

• Background :

  LCAT is an extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in its gene have been found to cause fish-eye disease as well as LCAT deficiency.This gene encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in this gene have been found to cause fish-eye disease as well as LCAT deficiency.

• NCBI Gene ID :

  3931

• Swiss Prot :

  P04180

• Accession Number :

  NP_000220

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat, Dog

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LCAT.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Membrane, Signal Transduction

• Purification :

  Antibody is purified by protein A chromatography method.

• Positive Control :

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store LCAT antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  48 kDa

• Applications Notes :

  LCAT antibody can be used for detection of LCAT by ELISA at 1:312500. LCAT antibody can be used for detection of LCAT by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  LCAT

• NCBI Official Name :

  Lecithin-cholesterol acyltransferase

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Calabresi, L., (2005) Arterioscler. Thromb. Vasc. Biol. 25 (9), 1972-1978.

• Other Product Names :

  LCAT

• Tested Applications :

  ELISA, WB

• Protein ID :

  4557892

• Physical Properties :

  Liquid