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SLC22A1 Antibody

CAT: 0223-29-592Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-29-592Size:100 µL
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Background
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. SLC22A1 contains twelve putative transmembrane domains and is a plasma integral membrane protein.Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.
NCBI Gene ID
6580
Swiss Prot
O15245
Accession Number
NP_003048
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC22A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SLC22A1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
61 kDa, 56 kDa
Applications Notes
SLC22A1 antibody can be used for detection of SLC22A1 by ELISA at 1:62500. SLC22A1 antibody can be used for detection of SLC22A1 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SLC22A1
NCBI Official Name
Solute carrier family 22 (organic cation transporter), member 1
NCBI Organism
Homo sapiens
Background Reference 01
Bourdet, D.L., (2005) J. Pharmacol. Exp. Ther. 315 (3), 1288-1297.
Other Product Names
SLC22A1, HOCT1, OCT1, oct1_cds
Tested Applications
ELISA, WB, IHC
Protein ID
4506999
Physical Properties
Liquid

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