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SLC22A5 Antibody

CAT: 0223-15-729Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-15-729Size:100 µL
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Background
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. Alternative splicing of this gene results in multiple transcript variants.
NCBI Gene ID
6584
Swiss Prot
O76082
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human SLC22A5
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Fragment
IgG
Symbol
SLC22A5
NCBI Official Name
Solute carrier family 22 member 5
NCBI Organism
Homo sapiens
Other Product Names
CDSP, OCTN2, solute carrier family 22 member 5, high-affinity sodium dependent carnitine cotransporter, organic cation/carnitine transporter 2
Tested Applications
WB, IHC
Physical Properties
Liquid

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