BHMT Antibody

• Background:

  BHMT is a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in its gene could lead to hyperhomocyst (e) inemia, but such a defect has not yet been observed.Betaine-homocysteine methyltransferase is a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in BHMT could lead to hyperhomocyst (e) inemia, but such a defect has not yet been observed.

• NCBI Gene ID:

  635

• Swiss Prot:

  Q93088

• Accession Number:

  NP_001704

• Host:

  Rabbit

• Reactivity:

  Human, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BHMT.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. XBL-10409 - Fetal Liver Tissue Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store BHMT antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  45 kDa

• Applications Notes:

  BHMT antibody can be used for detection of BHMT by ELISA at 1:312500. BHMT antibody can be used for detection of BHMT by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  BHMT

• NCBI Official Name:

  Betaine--homocysteine S-methyltransferase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Castro, C., (2004) Biochemistry 43 (18), 5341-5351.

• Other Product Names:

  BHMT, BHMT1, HEL-S-61p

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  157266337

• Physical Properties:

  Liquid