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MAT1A Antibody

CAT: 0223-29-562Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-29-562Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MAT1A catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. MAT1A is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in its gene are associated with methionine adenosyltransferase deficiency.This gne encodes methionine adenosyltransferase I (alpha isoform), which catalyzes the formation of S-adenosylmethionine from methionine and ATP. Methionine adenosyltransferase deficiency is caused by recessive and dominant mutations, the latter identified in autosomal dominant persistant hypermethioninemia.
NCBI Gene ID
4143
Swiss Prot
Q00266
Accession Number
NP_000420
Host
Rabbit
Reactivity
Human, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAT1A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. XBL-10409 - Fetal Liver Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MAT1A antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
44 kDa
Applications Notes
MAT1A antibody can be used for detection of MAT1A by ELISA at 1:1562500. MAT1A antibody can be used for detection of MAT1A by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
MAT1A
NCBI Official Name
Methionine adenosyltransferase I, alpha
NCBI Organism
Homo sapiens
Background Reference 01
Oh, J.H., (2005) Mamm. Genome 16 (12), 942-954.
Other Product Names
MAT1A, MAT, MATA1, SAMS, SAMS1
Tested Applications
ELISA, WB
Protein ID
4557737
Physical Properties
Liquid

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