SLBP Antibody

• Background:

  SLBP binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.

• NCBI Gene ID:

  7884

• Swiss Prot:

  Q14493

• Accession Number:

  NP_006518

• Host:

  Rabbit

• Reactivity:

  Human, Dog, Zebrafish

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLBP.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SLBP antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  30 kDa

• Applications Notes:

  SLBP antibody can be used for detection of SLBP by ELISA at 1:312500. SLBP antibody can be used for detection of SLBP by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  SLBP

• NCBI Official Name:

  Stem-loop binding protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Borchers, C.H., (2006) Proc. Natl. Acad. Sci. U.S.A. 103 (9), 3094-3099.

• Other Product Names:

  SLBP, HBP

• Tested Applications:

  ELISA, WB

• Protein ID:

  5729862

• Physical Properties:

  Liquid