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KARS Antibody

CAT: 0223-29-355Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-29-355Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
NCBI Gene ID
3735
Swiss Prot
Q15046
Accession Number
NP_005539
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KARS.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store KARS antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
66 kDa
Applications Notes
KARS antibody can be used for detection of KARS by ELISA at 1:312500. KARS antibody can be used for detection of KARS by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
KARS
NCBI Official Name
Lysyl-tRNA synthetase
NCBI Organism
Homo sapiens
Background Reference 01
Halwani, R., (2004) J. Virol. 78 (14), 7553-7564.
Other Product Names
KARS, KRS, KARS1, KARS2, CMTRIB, DFNB89
Tested Applications
ELISA, WB, IHC
Protein ID
5031815
Physical Properties
Liquid

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