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TARBP2 Antibody

CAT: 0223-29-327Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-29-327Size:100 µL
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Background
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TARBP2 binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein.
NCBI Gene ID
6895
Swiss Prot
Q8WY33
Accession Number
AAL55731
Host
Rabbit
Reactivity
Human, Mouse, Rat, Zebrafish
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TARBP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TARBP2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
8 kDa, 37 kDa, 39 kDa, 37 kDa
Applications Notes
TARBP2 antibody can be used for detection of TARBP2 by ELISA at 1:312500. TARBP2 antibody can be used for detection of TARBP2 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TARBP2
NCBI Official Name
TAR (HIV-1) RNA binding protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Bannwarth, S., J. Biol. Chem. 276 (52), 48803-48813 (2001) .
Other Product Names
TARBP2, LOQS, TRBP, TRBP1, TRBP2
Tested Applications
ELISA, WB
Protein ID
18027283
Physical Properties
Liquid

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