CUGBP2 Antibody

• Background:

  Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation.Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Alternative splicing results in multiple transcript variants encoding different isoforms.

• NCBI Gene ID:

  10659

• Swiss Prot:

  Q96RQ6

• Accession Number:

  NP_006552

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog, Zebrafish

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CUGBP2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CUGBP2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  56 kDa, 52 kDa, 54 kDa, 52 kDa, 52 kDa, 52 kDa

• Applications Notes:

  CUGBP2 antibody can be used for detection of CUGBP2 by ELISA at 1:312500. CUGBP2 antibody can be used for detection of CUGBP2 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CELF2

• NCBI Official Name:

  CUGBP, Elav-like family member 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Han, J. (2005) (er) Nucleic Acids Res. 33 (9), 2769-2780.

• Other Product Names:

  CUGBP2, ETR3, ETR-3, NAPOR, CUGBP2, BRUNOL3

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  134152680

• Physical Properties:

  Liquid