PEG3 Antibody

• Background:

  PEG3 induces apoptosis in cooperation with SIAH1A and acts as a mediator between TP53/p53 and BAX in a neuronal death pathway that is activated by DNA damage. PEG3 acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. PEG3 also possesses a tumor suppressing activity in glioma cells.

• NCBI Gene ID:

  5178

• Swiss Prot:

  Q9GZU2

• Accession Number:

  NP_006201

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PEG3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Cancer

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  A204 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PEG3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  181 kDa

• Applications Notes:

  PEG3 antibody can be used for detection of PEG3 by ELISA at 1:312500. PEG3 antibody can be used for detection of PEG3 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  PEG3

• NCBI Official Name:

  Paternally expressed 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Dowdy, S.C., et al., (2005) Gynecol. Oncol. 99 (1), 126-134.

• Other Product Names:

  PEG3, PW1, ZNF904, ZSCAN24, ZKSCAN22

• Tested Applications:

  ELISA, WB

• Protein ID:

  33354285

• Physical Properties:

  Liquid