TP73 Antibody

• Background :

  TP73 belongs to the p53 family. It participates in the apoptotic response to DNA damage. When overproduced, it activates transcription from p53-responsive promoters and induces apoptosis. TP53 may be a tumor suppressor protein.

• NCBI Gene ID :

  7161

• Swiss Prot :

  O15350-2

• Accession Number :

  CAA72219

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TP73.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Transcription, Cell Cycle, Cancer, Apoptosis

• Purification :

  Antibody is purified by protein A chromatography method.

• Positive Control :

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TP73 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  55 kDa, 70 kDa

• Applications Notes :

  TP73 antibody can be used for detection of TP73 by ELISA at 1:312500. TP73 antibody can be used for detection of TP73 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  TP73

• NCBI Official Name :

  Tumor protein p73

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Kaghad, M., (1997) Cell 90 (4), 809-819.

• Other Product Names :

  TP73, P73

• Tested Applications :

  ELISA, WB

• Protein ID :

  2370177

• Physical Properties :

  Liquid