TP53BP2 Antibody

• Background:

  TP53BP2 is a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. TP53BP2 contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. TP53BP2 is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family.

• NCBI Gene ID:

  7159

• Swiss Prot:

  Q13625

• Accession Number:

  NP_001026855

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TP53BP2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Cancer

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. XBL-10426 - Fetal Thymus Tissue Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TP53BP2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  124 kDa, 111 kDa

• Applications Notes:

  TP53BP2 antibody can be used for detection of TP53BP2 by ELISA at 1:1562500. TP53BP2 antibody can be used for detection of TP53BP2 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  TP53BP2

• NCBI Official Name:

  Tumor protein p53 binding protein, 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ju, H., et al., (2005) Int. J. Cancer 117 (6), 957-960.

• Other Product Names:

  TP53BP2, BBP, 53BP2, ASPP2, P53BP2, PPP1R13A

• Tested Applications:

  ELISA, WB

• Protein ID:

  112799849

• Physical Properties:

  Liquid