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NR1D2 Antibody

CAT: 0223-28-892Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-28-892Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NR1D2 can interact with NCOA5 coactivator, leading to a strong increase of transcription of target genes. NR1D2 also binds to the sequences 5'-AATGTAGGTCA-3' and 5'-ATAACTAGGTCA-3' and acts as a potent competitive transcriptional silencer and negative regulator of RORalpha mediated trans-activation. NR1D2 may play different roles in metabolism, inflammation, and circadian cycling in the organ-specific manner in homeostasis.
NCBI Gene ID
9975
Swiss Prot
Q14995
Accession Number
NP_005117
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR1D2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NR1D2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
65 kDa
Applications Notes
NR1D2 antibody can be used for detection of NR1D2 by ELISA at 1:312500. NR1D2 antibody can be used for detection of NR1D2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
NR1D2
NCBI Official Name
Nuclear receptor subfamily 1, group D, member 2
NCBI Organism
Homo sapiens
Background Reference 01
Wang, J., (2008) Biochim. Biophys. Acta 1783 (2), 224-236.
Other Product Names
NR1D2, BD73, EAR-1r, HZF2, Hs.37288, RVR, EAR-1R
Tested Applications
ELISA, WB
Protein ID
224177491
Physical Properties
Liquid

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