IRF1 Antibody

IRF1 is interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.

3659

P10914

NP_002189

Human, Mouse, Rat, Dog

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IRF1.

Unconjugated

Primary Antibodies

Transcription, Cell Cycle, Cancer, Signal Transduction, Immunology, , Inflammasomes

Antibody is purified by peptide affinity chromatography method.

Cat. No. 1211 - HepG2 Cell Lysate

Batch dependent

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

None

Blue Ice

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store IRF1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

37 kDa

IRF1 antibody can be used for detection of IRF1 by ELISA at 1:62500. IRF1 antibody can be used for detection of IRF1 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

IRF1

Interferon regulatory factor 1

Homo sapiens

Kumar, A., (2005) J. Biol. Chem. 280 (52), 42619-42626.

IRF1, IRF-1, MAR

ELISA, WB

4504721