IRF5 Antibody

• Background :

  This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment.

• NCBI Gene ID :

  3663

• Swiss Prot :

  Q13568

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human IRF5 (NP_001092097.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Chemokines & Cytokines, Immunology, Innate Immunity, Transcription

• Purification :

  Affinity purification

• Positive Control :

  THP-1

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 56kDa

• Fragment :

  IgG

• Symbol :

  IRF5

• Positive Control 2 :

  Rat thymus

• NCBI Official Name :

  Interferon regulatory factor 5

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  IRF5, SLEB10

• Tested Applications :

  WB, IHC

• Physical Properties :

  Liquid