TGFB1 Antibody

• Background:

  Tgfb1 is a multifunctional protein that control proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGFB1 and essentially all of them have specific receptors for this protein. It regulates the actions of many other growth factors and determines a positive or negative direction of their effects. It plays an important role in bone remodelling. It is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.

• NCBI Gene ID:

  21803

• Swiss Prot:

  P04202

• Accession Number:

  NP_035707

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse TGFB1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Cancer

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  SP2/0 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TGFB1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  43 kDa

• Applications Notes:

  TGFB1 antibody can be used for detection of TGFB1 by ELISA at 1:1562500. TGFB1 antibody can be used for detection of TGFB1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  TGFB1

• NCBI Official Name:

  Transforming growth factor, beta 1

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Cheon, S.S., (2006) FASEB J. 20 (6), 692-701.

• Other Product Names:

  TGFB1, Tgfb, Tgfb-1, TGFbeta1, TGF-beta1

• Tested Applications:

  ELISA, WB

• Protein ID:

  6755775

• Physical Properties:

  Liquid