MESP2 Antibody

• Background:

  Somite boundaries formed during embryogenesis, at the interface between Notch1-activated and -repressed domains. Genetic and biochemical studies indicate that this interface is generated by suppression of Notch activity by mesoderm posterior 2 (Mesp2) through induction of the lunatic fringe gene (Lfng) . It is proposed that the oscillation of Notch activity is arrested and translated in the wavefront by Mesp2.

• NCBI Gene ID:

  17293

• Swiss Prot:

  O08574

• Accession Number:

  NP_032615

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MESP2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  SP2/0 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MESP2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  41 kDa

• Applications Notes:

  MESP2 antibody can be used for detection of MESP2 by ELISA at 1:62500. MESP2 antibody can be used for detection of MESP2 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  MESP2

• NCBI Official Name:

  Mesoderm posterior 2

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Morimoto, M., et al., (2005) Nature 435 (7040), 354-359.

• Other Product Names:

  MESP2, bHLHc6

• Tested Applications:

  ELISA, WB

• Protein ID:

  111955348

• Physical Properties:

  Liquid