Products for Research Use Only
RegisterLogin

SCN5A Antibody

CAT: 0223-28-312Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-28-312Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
SCN5A is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. The protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram.The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. The encoded protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in two transcript variants encoding separate isoforms which differ by a single amino acid. Mutation nomenclature has been assigned with respect to the longer isoform.
NCBI Gene ID
6331
Swiss Prot
Q8IZC9
Accession Number
NP_000326
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Zebrafish
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SCN5A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
SW620 Cell Lysate using SCN5A antibody at 0.25 μ g/mL (8% gel) .
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SCN5A antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
222 kDa, 227 kDa, 36 kDa
Applications Notes
SCN5A antibody can be used for detection of SCN5A by ELISA at 1:312500. SCN5A antibody can be used for detection of SCN5A by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SCN5A
NCBI Official Name
Sodium channel, voltage-gated, type V, alpha subunit
NCBI Organism
Homo sapiens
Background Reference 01
Shah, V.N., (2006) Proc. Natl. Acad. Sci. U.S.A. 103 (10), 3592-3597.
Other Product Names
SCN5A, CDCD2, CMD1E, CMPD2, HB1, HB2, HH1, IVF, LQT3, Nav1.5, SSS1, VF1, HBBD, ICCD, PFHB1
Tested Applications
ELISA, WB, IHC
Protein ID
30089970
Physical Properties
Liquid

Related Products

CatalogName
46-343PSCN5A Peptide
42-840PSCN5A Peptide
13-732SCN2A Antibody
13-423SCN7A Antibody
13-412SCN3A Antibody
13-368SCN8A Antibody
42-870PSCN9A Peptide
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody

Alternative Products

CatalogName
70R-30755SCN5A antibody

Popular Products