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KCND3 Antibody

CAT: 0223-28-250Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-28-250Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s) . KCND3 encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential.
NCBI Gene ID
3752
Swiss Prot
Q9UK17-2
Accession Number
NP_751948
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCND3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store KCND3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
70 kDa
Applications Notes
KCND3 antibody can be used for detection of KCND3 by ELISA at 1:12500. KCND3 antibody can be used for detection of KCND3 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
KCND3
NCBI Official Name
Potassium voltage-gated channel, Shal-related subfamily, member 3
NCBI Organism
Homo sapiens
Background Reference 01
Hatano, N., et al., (2004) J. Biol. Chem. 279 (7), 5450-5459.
Other Product Names
KCND3, KV4.3, SCA19, SCA22, KCND3L, KCND3S, KSHIVB
Tested Applications
ELISA, WB
Protein ID
27436986
Physical Properties
Liquid

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