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NFKBIB Antibody

CAT: 0223-28-111Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-28-111Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Inhibition of NFkappa-B activity by the hepatitis C virus core protein might be related to its physical interaction with and interrupted nuclear localization of IKKbeta. Increased nuclear factor-kappaB (NF-kB) activity in the amnion during labor is associated with an increase in the expression of NF-kBp65 and of the NF-kB binding proteins IkBa, IkBb-1 and IkBb-2. IkappaBbeta may be a novel target for transcription factors of the HMG-box SRY/Sox family and imply a potential role for NF-kappaB/IkappaBbeta in spermatogenesis.
NCBI Gene ID
4793
Swiss Prot
Q15653
Accession Number
NP_002494
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NFKBIB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer, Signal Transduction
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NFKBIB antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
38 kDa
Applications Notes
NFKBIB antibody can be used for detection of NFKBIB by ELISA at 1:62500. NFKBIB antibody can be used for detection of NFKBIB by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
NFKBIB
NCBI Official Name
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NCBI Organism
Homo sapiens
Background Reference 01
Lee, Y., et al., (2003) Mol. Hum. Reprod. 9 (4), 213-218.
Other Product Names
NFKBIB, IKBB, TRIP9
Tested Applications
ELISA, WB
Protein ID
21361135
Physical Properties
Liquid

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