CBX1 Antibody

CAT: 0223-28-089Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-28-089Size:100 µL
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Background
CBX1 is the component of heterochromatin. CBX1 recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. CBX1 interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.Heterochromatin protein-1 (HP1) is localized at heterochromatin sites, where it mediates gene silencing.
NCBI Gene ID
10951
Swiss Prot
P83916
Accession Number
NP_006798
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CBX1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CBX1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
21 kDa
Applications Notes
CBX1 antibody can be used for detection of CBX1 by ELISA at 1:62500. CBX1 antibody can be used for detection of CBX1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CBX1
NCBI Official Name
Chromobox homolog 1
NCBI Organism
Homo sapiens
Background Reference 01
Verschure, P.J., et al., (2005) Mol. Cell. Biol. 25 (11), 4552-4564.
Other Product Names
CBX1, CBX, M31, MOD1, p25beta, HP1-BETA, HP1Hsbeta, HP1Hs-beta
Tested Applications
ELISA, WB
Protein ID
5803076
Physical Properties
Liquid

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